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2011, 03, v.40 407-412
外源化学物对细胞线粒体呼吸链复合体Ⅰ损伤的研究进展
基金项目(Foundation): 国家自然科学基金项目(No.30972551)
邮箱(Email):
DOI: 10.19813/j.cnki.weishengyanjiu.2011.03.040
发布时间: 2011-05-30
出版时间: 2011-05-30
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摘要:

<正>线粒体复合体Ⅰ位于线粒体内膜上,又称NADH-CoQ氧化还原酶,由45个亚单位组成[1]。单粒子电子显微镜显示无论是原核细胞还是真核细胞的复合体Ⅰ均有1个L型整体结构[2]。复合体Ⅰ的疏水性跨膜臂镶嵌在线粒体内膜中,而亲水性头部伸入线粒体基质中。膜表面臂包含有1个以核黄素单核苷酸(FMN)为辅基的黄素蛋白、8个以Fe-S簇为辅基的

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参考文献

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基本信息:

DOI:10.19813/j.cnki.weishengyanjiu.2011.03.040

中图分类号:R114

引用信息:

[1]李艳红,钟才高.外源化学物对细胞线粒体呼吸链复合体Ⅰ损伤的研究进展[J].卫生研究,2011,40(03):407-412.DOI:10.19813/j.cnki.weishengyanjiu.2011.03.040.

基金信息:

国家自然科学基金项目(No.30972551)

发布时间:

2011-05-30

出版时间:

2011-05-30

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