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机体中的免疫系统能识别异常细胞并进行清除,但肿瘤仍能在人体内发生、发展、转移,表明肿瘤具有免疫逃逸能力。明确肿瘤免疫逃逸机制是免疫治疗的突破口。本文综述近年来关于肿瘤免疫逃逸方面的研究进展,从肿瘤细胞自身的修饰、代谢异常,以及免疫细胞与肿瘤微环境中的基质细胞、缺氧环境等方面进行阐述,拟为肿瘤治疗提供思路。
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基本信息:
DOI:10.19813/j.cnki.weishengyanjiu.2018.02.031
中图分类号:R730.3
引用信息:
[1]程吉华,赵德强.肿瘤免疫逃逸机制研究进展[J].卫生研究,2018,47(02):330-334.DOI:10.19813/j.cnki.weishengyanjiu.2018.02.031.
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2018-03-30