卫生研究

参考文献

[1] HALMO L,NAPPE T M.Lead toxicity[M].Treasure Island:StatPearls Publishing,2021.

[2] ROCHA A,TRUJILLO K A.Neurotoxicity of low-level lead exposure:history,mechanisms of action,and behavioral effects in humans and preclinical models[J].Neurotoxicology,2019,73:58-80.

[3] 国家卫生健康委员会.中国卫生健康事业发展统计公报[R].北京：国家卫生健康委员会，2018.

[4] KESHRI S,GOEL A K,GARG A K.Reversal of acute lead encephalopathy in a child[J].Cureus,2021,13(5):e15155.

[5] BAKULSKI K M,SEO Y A,HICKMAN R C,et al.Heavy metals exposure and Alzheimer’s disease and related dementias[J].J Alzheimers Dis,2020,76(4):1215-1242.

[6] KARRI V,RAMOS D,MARTINEZ J B,et al.Differential protein expression of hippocampal cells associated with heavy metals (Pb,As,and MeHg) neurotoxicity:deepening into the molecular mechanism of neurodegenerative diseases[J].J Proteomics,2018,187:106-125.

[7] HUAT T J,CAMATS-PERNA J,NEWCOMBE E A,et al.Metal toxicity links to Alzheimer’s disease and neuroinflammation[J].J Mol Biol,2019,431(9):1843-1868.

[8] FUNAMOTO S,TAGAMI S,OKOCHI M,et al.Successive cleavage of β-amyloid precursor protein by γ-secretase[J].Semin Cell Dev Biol,2020,105:64-74.

[9] BUTTERFIELD D A.Ubiquitin carboxyl-terminal hydrolase L-1 in brain:focus on its oxidative/nitrosative modification and role in brains of subjects with Alzheimer disease and mild cognitive impairment[J].Free Radic Biol Med,2021,177:278-286.

[10] NALIVAEVA N N,ZHURAVIN I A,TURNER A J.Neprilysin expression and functions in development,ageing and disease[J].Mech Ageing Dev,2020,192:111363.

[11] WU J,BASHA M R,BROCK B,et a1.Alzheimer’s disease(AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead(Pb):evidence for a developmental origin and environmental link for AD[J].J Neurosci,2008,28 (1):3-9.

[12] BAI L,LIU R,WANG R,et al.Attenuation of Pb-induced Aβ generation and autophagic dysfunction via activation of SIRT1:neuroprotective properties of resveratrol[J].Ecotoxicol Environ Saf,2021,222:112511.

[13] QIAO A,LI J,HU Y,et al.Reduction BACE1 expression via suppressing NF-κB mediated signaling by tamibarotene in a mouse model of Alzheimer’s disease[J].IBRO Neurosci Rep,2021,10:153-160.

[14] WANG Y,HU Y,WU Z,et al.Latent role of in vitro Pb exposure in blocking Aβ clearance and triggering epigenetic modifications[J].Environ Toxicol Pharmacol,2019,66:14-23.

[15] 李星.铅致阿尔茨海默症样变神经毒性及对相关通路蛋白表达的影响[D].郑州：郑州大学，2017.

[16] OTERO-GARCIA M,MAHAJANI S U,WAKHLOO D,et al.Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease[J].Neuron,2022,110(18):2929-2948.

[17] WANG S,JIANG Y,LIU Y,et al.Ferroptosis promotes microtubule-associated protein tau aggregation via GSK-3β activation and proteasome inhibition[J].Mol Neurobiol,2022,59(3):1486-1501.

[18] BROTZAKIS Z F,LINDSTEDT P R,TAYLOR R J,et al.A Structural ensemble of a tau-microtubule complex reveals regulatory tau phosphorylation and acetylation mechanisms[J].ACS Cent Sci,2021,7(12):1986-1995.

[19] RAHMAN A,BREW B J,GUILLEMIN G J.Lead dysregulates serine/threonine protein phosphatases in human neurons[J].Neurochem Res,2011,36(2):195-204.

[20] 冯昶，范广勤，黎砚书，等.长期铅暴露致大鼠神经退行性改变[C]//中国毒理学会第六届全国毒理学大会论文集.广州：中国毒理学会，2013:196-197.

[21] 宋靖宇，黎砚书，陈英，等.铅暴露对大鼠海马组织APP和tau蛋白表达影响[J].中国公共卫生，2016,32(6):778-781.

[22] AHMED N Y,KNOWLES R,DEHORTER N.New insights into cholinergic neuron diversity[J].Front Mol Neurosci,2019,12:204.

[23] WAXENBAUM J A,REDDY V,VARACALLO M.Anatomy,autonomic nervous system[M].Treasure Island:StatPearls Publishing,2022.

[24] HAMPEL H,MESULAM M M,CUELLO A C,et al.Revisiting the cholinergic hypothesis in alzheimer’s disease:emerging evidence from translational and clinical research[J].J Prev Alzheimers Dis,2019,6(1):2-15.

[25] BEN-AZU B,ADEBAYO O G,WOPARA I,et al.Lead acetate induces hippocampal pyramidal neuron degeneration in mice via up-regulation of executioner caspase-3,oxido-inflammatory stress expression and decreased BDNF and cholinergic activity:reversal effects of Gingko biloba supplement [J].J Trace Elem Med Biol,2021,71:126919.

[26] 严伟伟，贾仰民，韩静茵，等.铅暴露对小鼠学习记忆能力的影响及机制研究[J].浙江中西医结合杂志，2017,27(1):21-23.

[27] WANG T,ZHANG J,XU Y.Epigenetic basis of lead-induced neurological disorders[J].Int J Environ Res Public Health,2020,17(13):4878.

[28] MATTEI A L,BAILLY N,MEISSNER A.DNA methylation:a historical perspective[J].Trends Genet,2022,38(7):676-707.

[29] ZHANG Y,SUN Z,JIA J,et al.Overview of histone modification[J].Adv Exp Med Biol,2021,1283:1-16.

[30] PANNI S,LOVERING R C,PORRAS P,et al.Non-coding RNA regulatory networks[J].Biochim Biophys Acta Gene Regul Mech,2020,1863(6):194417.

[31] MANI M S,KABEKKODU S P,JOSHI M B,et al.Ecogenetics of lead toxicity and its influence on risk assessment[J].Hum Exp Toxicol,2019,38:1031-1059.

[32] BIHAQI S W,HUANG H,WU J,et al.Infant exposure to lead (Pb) and epigenetic modifications in the aging primate brain:implications for Alzheimer’s disease[J].J Alzheimers Dis,2011,27(4):819-833.

[33] 李琼，王瑞克，白林，等.SIRT1调节DNA甲基化对铅暴露PC12细胞损伤的调控作用[C]//第27届中国大气环境科学与技术大会暨中国环境科学学会大气环境分会2021年学术年会论文集.北京：中国环境科学学会，2021:83-83.

[34] LUO M,XU Y,CAI R,et al.Epigenetic histone modification regulates developmental lead exposure induced hyperactivity in rats[J].Toxicol Lett,2014,225(1):78-85.

[35] 何杨，王凯，庞妍，等.铅暴露工人相关基因甲基化与遗传损伤关系的研究[J].中国工业医学杂志，2020,33(4):304-308.

[36] MATSUYAMA H,SUZUKI H I.Systems and synthetic microrna biology:from biogenesis to disease pathogenesis[J].Int J Mol Sci,2019,21(1):132.

[37] AN J,CAI T,CHE H,et al.The changes of miRNA expression in rat hippocampus following chronic lead exposure[J].Toxicol Lett,2014,229(1):158-166.

[38] HUANG A,ZHENG H,WU Z,et al.Circular RNA-protein interactions:functions,mechanisms,and identification[J].Theranostics,2020,10(8):3503-3517.

[39] MEHTA S L,DEMPSEY R J,VEMUGANTI R.Role of circular RNAs in brain development and CNS diseases[J].Prog Neurobiol,2020,186:101746.

[40] PIWECKA M,GLA?AR P,HERNANDEZ-MIRANDA L R,et al.Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function[J].Science,2017,357(6357):eaam8526.