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目的 探索在中老年高血压患者中，中老年人中高血压共病模式和社会参与的交互作用和抑郁症状的关系。方法 使用中国健康与养老追踪调查2015、2018和2020年全国调查数据，纳入2786名45岁及以上的中老年高血压患者。使用频数和百分比描述基线特征。采用广义估计方程模型分析数据，以中老年抑郁症状作为因变量构建广义估计方程模型，采用单因素和多因素分析高血压共病模式和社会参与对抑郁症状的影响，并分析高血压共病模式和社会参与的交互作用对抑郁症状的影响。结果 在2786名中老年高血压患者的基线特征中，高血压共病患者有2319例(83.24%),有社会参与者1558例(55.92%)。中老年人抑郁症状的单因素广义估计方程分析结果显示，高血压共病的中老年人患抑郁症状的风险高于高血压无共病者(OR=2.31,95%CI 1.97～2.71,P<0.01),有社会参与的中老年人患抑郁症状的风险低于无社会参与者(OR=0.71,95%CI 0.64～0.78,P<0.01)。中老年人抑郁症状的多因素广义估计方程分析结果显示，高血压共病的中老年人患抑郁症状的风险高于高血压无共病者(OR=2.06,95%CI 1.75～2.41,P<0.01),有社会参与的中老年人患抑郁症状的风险低于无社会参与者(OR=0.78,95%CI 0.70～0.87,P<0.01)。高血压共病和社会参与的交互作用与中老年人抑郁症状的分析结果显示，高血压共病无社会参与的中老年人患抑郁症状风险高于高血压无共病无社会参与者(OR=2.20,95%CI 1.78～2.72,P<0.01)。结论 中国中老年高血压人群共病情况严重，高血压共病人群进行社会参与可以降低抑郁症状患病的风险。
Abstract：OBJECTIVE To explore the relationship between hypertensive comorbidity patterns and social participation and depressive symptoms in middle-aged and elderly hypertensive patients.METHODS Using the data from the 2015, 2018 and 2020 of the China Health and Retirement Longitudinal Study, 2786 middle and elderly adults aged 45 and above with hypertension were included. Data analysis was performed in Stata 17.0 statistical software, using frequency and percentage to describe baseline characteristics. The generalized estimation equation(GEE) was used to to analyze the data, and GEE was constructed with the depressive symptoms of middle and elderly people as the dependent variable. The unifactorial and multifactorial analysis of the effects of hypertensive comorbidity patterns and social participation on depressive symptoms, and the influence of the interaction between hypertensive comorbidity patterns and social participation on depressive symptoms were analyzed.RESULTS Among the baseline characteristics of 2786 middle and older adults with hypertension, 2319(83.24%) had hypertensive comorbidity and 1558(55.92%) had social participant. The result of unifactorial GEE analysis of depressive symptoms in middle and older adults showed that the risk of depressive symptoms was higher in hypertensive comorbidity than in hypertension without comorbidity(OR=2.31, 95%CI 1.97-2.71, P<0.01), and lower in middle and older adults with social participation than in those without social participation(OR=0.71, 95%CI 0.64-0.78, P<0.01).The result of multifactorial GEE analysis of depressive symptoms in middle and older adults showed that the risk of depressive symptoms was higher in hypertensive comorbidity than in hypertension without comorbidity(OR=2.06, 95%CI 1.75-2.41, P<0.01), and lower in middle and older adults with social participation than in those without social participation(OR=0.78, 95%CI 0.70-0.87, P<0.01). Analysis of the interaction of hypertensive comorbidity and social participation on depressive symptoms in middle and older adults showed that middle and older adults with hypertensive comorbidity and no social participation had a 2.20 times higher risk of depressive symptoms than those with hypertension without comorbidity and no social participation(OR=2.20, 95%CI 1.78-2.72, P<0.01).CONCLUSION Comorbidity is severe in the hypertensive population, and social participation in the hypertensive comorbidity population may reduce the risk of developing depressive symptoms.
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基本信息:
DOI：10.19813/j.cnki.weishengyanjiu.2024.05.002
中图分类号:R749.4;R544.1
引用信息:
[1]崔曼,王娟,邓淼,等.高血压共病模式和社会参与交互作用对中国中老年人抑郁症状的影响[J].卫生研究,2024,53(05):694-700.DOI:10.19813/j.cnki.weishengyanjiu.2024.05.002.
基金信息:
河南省自然科学基金(No.182300410303); 河南省高等院校重点科研项目(No.23B330005)
2024-09-05
2024-09-05