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应用 Northern斑点杂交方法研究氯化镉对大鼠肝细胞原癌基因 c- fos、c- jun表达的影响。结果表明 ,5、10和 2 0 μmol/ kg氯化镉腹腔一次注射后 ,大鼠肝细胞 c- fos、c- jun m RNA较对照组明显增多。结果提示 ,氯化镉可以引起大鼠在体肝细胞原癌基因 c- fos、c- jun表达增强
Abstract：The effects of cadmium chloride on the expression of proto oncogene c fos and c jun of rat liver cells were studied with Northern dot hybridization. The results showed that at the dose of 5, 10 or 20μmol/kg of cadmium chloride, the expression of proto oncogene c fos and c jun could be induced obviously.
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基本信息:
中图分类号:R735.7
引用信息:
[1]余日安,陈学敏,鲁文清.镉对大鼠肝细胞原癌基因c-fos、c-jun表达的影响[J].卫生研究,2000(06):364-365.
基金信息:
国家自然科学基金资助项目!(No.396 70 6 2 6 )
2000-11-20
2000-11-20