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黄酮类化合物广泛存在于植物类食物中,具有多种生理活性。然而,现在关于黄酮类化合物毒副作用的研究发现,某些黄酮具有遗传毒性,还可能干扰甲状腺激素的合成;异黄酮的雌激素活性可能对动物和人的生长发育带来不良影响;黄酮还可能影响营养物质的吸收、药物代谢及神经行为。本文综述了黄酮类化合物毒性方面的研究进展。
Abstract：Flavonoids may be natural components came from many vegetables and fruits.A variety of heath effects of these compounds were found.However,a few safety studies indicated that certain adverse effects of these compounds could influence on human health,which could involve genotoxic/carcinogenic effects or interaction with thyroid hormone biosynthesis.Isoflavones' estrogenic activity could influence on sexual development of young animals and children.Furthermore,flavonoids could inhibit the absorption of some nutrients,interact with certain drug pharmacokinetics and affect neurobehavioral development.In this paper,the potential toxicities of flavonoids from recently published papers were reviewed.
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基本信息:
中图分类号:TS201
引用信息:
[1]汪何雅,赵显峰,王茵,等.黄酮类化合物的潜在毒性[J].卫生研究,2007(05):640-642.
2007-09-30
2007-09-30