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目的分析阿尔茨海默病患者尿液中17种游离氨基酸含量。方法采用病例-对照研究,收集34位阿尔茨海默病患者与31位健康老年人尿液样品,利用L-8800氨基酸自动分析仪测定尿液中17种游离氨基酸的含量。结果病例组和对照组尿液中Lys、Val、Thr和Ser含量有显著性差异(P<0.05);Asp和Glu的水平与对照组相比分别降低了31.06%和30.82%,差异无显著性(P>0.05)。结论阿尔茨海默病患者体内氨基酸代谢紊乱或障碍。
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基本信息:
DOI：10.19813/j.cnki.weishengyanjiu.2012.01.027
中图分类号:R749.16
引用信息:
[1]刘秀勤,张燕,王新红,等.阿尔茨海默病患者尿液中17种游离氨基酸的分析[J].卫生研究,2012,41(01):113-116.DOI:10.19813/j.cnki.weishengyanjiu.2012.01.027.
2012-01-30
2012-01-30