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目的了解重庆城区儿童青少年代谢综合征流行现状及其家庭影响因素。方法采用多阶段整群抽样,于2014年从重庆城区获得1309名10~17岁儿童青少年完成体格检查(包括身高、体重、腰围和血压)、血生化检查(包括空腹血糖、甘油三酯、总胆固醇、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇)及家庭影响因素问卷(包括孩子是否母乳喂养、分娩方式、出生体重、父母的文化程度、父母的身高体重、是否有高血压和糖尿病家族史等);采用中国儿童青少年代谢综合征定义和防治建议的标准进行代谢综合征的诊断。结果重庆城区儿童青少年代谢综合征检出率为5.5%,其中体重正常、超重和肥胖组代谢综合征检出率分别为0.6%、13.8%和41.2%。单因素分析提示,儿童青少年代谢综合征与父亲体质指数(χ2=8.237,P=0.016)、母亲体质指数(χ2=8.978,P=0.011)、父亲职业(χ2=7.742,P=0.021)、母亲职业(χ2=6.578,P=0.037)及高血压家族史(χ2=7.684,P=0.006)有关。多因素分析提示,父亲超重(OR=1.956,95%CI 1.1763.254)、母亲肥胖(OR=2.934,95%CI 1.2306.999)及有高血压家族史(OR=1.867,95%CI 1.1393.059)是儿童青少年代谢综合征的危险因素。结论重庆城区儿童青少年代谢综合征检出率较高;影响其发生的家庭因素主要是父亲超重、母亲肥胖及有高血压家族史。
Abstract:Objective To study the prevalence and family factors on metabolic syndrome( MS) in children and adolescents for Chongqing City. Methods Multi-stage cluster sampling was used to recruit 1309 children and adolescents between 10 and 17 years old for physical examination( height, weight, waist circumference and blood pressure),blood biochemical examination( fasting plasma glucose,triglyceride,total cholesterol,high density lipoprotein cholesterol and low density lipoprotein cholesterol)and questionnaire for family factors( breast feeding, delivery mode, birth weight,education of parents,height and weight of parents,family history of hypertension and diabetes,and so on). MS was diagnosed by the definition of metabolic syndrome and prophylaxis and treatment proposal in Chinese children and adolescents. Results The prevalence of MS on children and adolescents in Chongqing city was 5. 5%,and among normal weight, overweight, and obese groups were 0. 6%, 13. 8% and 41. 2%,respectively. Univariate analysis showed BMI of father( χ2= 8. 237,P = 0. 016),BMI of mother( χ2= 8. 978,P = 0. 011), occupation of father( χ2= 7. 742,P = 0. 021),occupation of mother( χ2= 6. 578,P = 0. 037) and family history of hypertension( χ2=7. 684,P = 0. 006) were associated with MS. Logistic regression analysis showed father's overweight( OR = 1. 956,95% CI 1. 176-3. 254),mother's obesity( OR = 2. 934,95%CI 1. 230-6. 999) and family history of hypertension( OR = 1. 867,95% CI 1. 139-3. 059) were risk factors for MS. Conclusion The detection rate of MS on children and adolescents in Chongqing city is higher,and the mainly risk family factors are father's overweight,mother's obesity and family history of hypertension.
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基本信息:
DOI:10.19813/j.cnki.weishengyanjiu.2017.04.007
中图分类号:R181.3;R725.8
引用信息:
[1]程绪婷,王宏,袁保诚,等.2014年重庆城区儿童青少年代谢综合征及家庭影响因素[J].卫生研究,2017,46(04):557-562.DOI:10.19813/j.cnki.weishengyanjiu.2017.04.007.
基金信息:
卫生公益性行业科研专项(No.201202010)
2017-07-30
2017-07-30