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目的了解天津市农村40岁以上人群血脂状况,并分析其与血清肉毒碱棕榈酰基转移酶的相关性。方法采用多阶段整群随机抽样,从天津市农村地区抽取719名40岁以上的人群,采集空腹静脉血测定血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、肉毒碱棕榈酰基转移酶1A(CPT1A),对结果进行分析。结果血脂异常率为46.73%(336/719),男性为48.22%(163/338),女性为45.41%(173/381),差别无统计学意义。简单线性相关分析显示,CPT1A与TC、LDL-C的相关系数r分别为0.123和0.130(P<0.01);经多元线性回归分析后,只有LDL-C与CPT1A呈相关关系(P<0.01)。结论天津农村40岁以上人群血脂异常率偏高,血脂水平与血清肉毒碱棕榈酰基转移酶关系密切。
Abstract：Objective To explore the status of serum lipids and analyze its relationship with carnitine palmitoyl transferase 1A( CPT1A) in rural people over 40 in Tianjin,China. Methods By cluster multi-stratified sample of 719 people over 40 was investigated with a questionnaire from rural areas in Tianjin. And finally draw a conclusion based on data analysis from fasting blood and measured total cholesterol( TC),triglyceride( TG),high density lipoprotein cholesterol( HDL-C) and CPT1A. Results In this research,the rate of dyslipidemia was 46. 73%,in which 48. 22 percent male and45. 41 percent female,a nonsignificant difference. CPT1A correlated with TC,LDL-C were 0. 123 and 0. 130,with simple linear regression,and there was only significant difference between LDL-C and CPT1A by multiple regression analysis. Conclusion There is a high rate of dyslipidemia among the rural people over the age of 40 in Tianjin,and the CPT1A is closely associated with serum lipid.
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基本信息:
DOI：10.19813/j.cnki.weishengyanjiu.2014.02.012
中图分类号:R195
引用信息:
[1]周朋辉,张静姝,何宁,等.天津市农村40岁以上人群血脂水平与血清肉毒碱棕榈酰基转移酶的相关性研究[J].卫生研究,2014,43(02):228-232.DOI:10.19813/j.cnki.weishengyanjiu.2014.02.012.
基金信息:
2012年“达能营养中心膳食营养研究与宣教基金”; 天津市卫生系统攻关项目(No.13KG138)
2013-07-16
2013
2013-10-09
2013-11-08
2013
1
2014-03-30
2014-03-30