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目的分析深圳市孕妇妊娠不同阶段增重速率并探讨其与妊娠结局的关系。方法于2013年4—7月招募深圳市妇幼保健院进行常规产检的孕12周以内单胎健康孕妇(怀孕年龄20～35岁)为研究对象,前瞻性追踪调查孕期膳食摄入情况、生活行为方式、妊娠合并症以及新生儿出生结局,测量孕妇不同阶段体重和新生儿出生体格,获得421份有效资料进行分析。结果孕早期平均增重速率(0.05±0.15)kg/w,低于孕中期[(0.56±0.17)kg/w]和孕晚期[(0.54±0.22)kg/w],差异有统计学意义(P<0.01),孕中、晚期增重速率差异无统计学意义。多元线性回归分析结果显示,孕中期增重速率与新生儿出生体重、身长、头围呈正相关(β体重=0.31,P=0.002;β身长=0.82,P=0.007;β头围=0.72,P=0.016)。Logistic回归分析结果显示,孕中期增重速率与剖宫产率呈正相关(OR=3.59,95%CI 1.08～11.90);孕晚期增重速率与羊水异常发生率呈正相关(OR=13.04,95%CI 1.70～100.10),与妊娠期糖尿病发生率呈负相关(OR=0.001,95%CI 0～0.01)。结论 2013年深圳市孕妇孕期增重不合理现象较普遍;孕中期增重速率与新生儿出生体格呈正相关;孕中晚期增重过快或过缓增加不良妊娠结局的发生。
Abstract：OBJECTIVE To analyze the rates of weight gain during different trimesters of pregnancy and their associations with pregnancy outcomes in Shenzhen pregnant women. METHODS Healthy singleton pregnant women aged from 20 to 35, within 12 weeks of gestation, in the Shenzhen Maternal and Child Health Hospital for routine medical checkups were recruited. Information about their dietary intake and lifestyle behavior during pregnancy, pregnancy outcomes and neonatal birth outcomes were followed up prospectively, meanwhile maternal weight at per trimester and newborn birth physique were measured, and 421 valid cases were analyzed. RESULTS Significantly lower rate of weight gain in the 1 st trimester((0.05±0.15)kg/w) were observed than that in the 2 nd trimester((0.56±0.17)kg/w) and the 3 rd trimester((0.54±0.22)kg/w)(P<0.01). No significant difference was found for that between the 2 nd and 3 rd trimester(P>0.05). The multiple linear regression analysis showed positive correlations between maternal weight gain rate in the 2 nd trimester and the neonatal birth physique, including birth weight, birth length, and head circumference(βBW=0.31,P=0.002;βBL=0.82,P=0.007;βHC=0.72,P=0.016). Logistic regression analysis showed a positive relation between the rate of weight gain in the 2 nd and the incidence of cesarean section(OR=3.59,95%CI 1.08-11.90). The rate of weight gain in the 3 rd trimester turned out to be positively correlated with the incidence of abnormal amniotic fluid(OR=13.04,95%CI 1.70-100.10)and negatively correlated with the incidence of gestational diabetes(OR=0.001,95%CI 0-0.01). CONCLUSION The weight gain during pregnancy was unsatisfactory in most of Shenzhen women in 2013. The rate of weight gain in the 2 nd trimester was positively correlated to the birth physique of newborns. The excessive rapid and slow growth of weight gain during the 2 nd-3 rd trimester could both increase the risks of adverse pregnancy outcomes.
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基本信息:
DOI：10.19813/j.cnki.weishengyanjiu.2019.03.010
中图分类号:R715.3
引用信息:
[1]李艳会,罗惠萍,李宜静,等.2013年深圳市421例孕妇不同孕期增重速率及与妊娠结局的关系[J].卫生研究,2019,48(03):423-427+434.DOI:10.19813/j.cnki.weishengyanjiu.2019.03.010.
基金信息:
达能纽迪希亚生命早期营养
2019-05-21
2019-05-21