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目的 分析中国18岁及以上成年男性和女性饮酒与代谢综合征(MS)的关系。方法 以2010—2012年中国居民营养与健康状况监测为依托,采用与人口成比例的多阶段分层整群随机抽样方法选取102591名18岁及以上成年人,采用家庭询问调查问卷收集对象基本信息、健康相关行为和疾病史等数据,通过食物频率法收集调查对象的饮酒信息,代谢综合征的诊断采用NCEPATPⅢ标准。采用Logistic回归分析饮酒与MS的关系。采用限制性立方样条模型分析饮酒与MS的剂量-反应关系。结果 中国18岁及以上成年人的饮酒率为33.66%;与不饮酒者相比,男性每次饮酒量≤20 g人群MS患病率较低(OR=0.77,95%CI 0.66～0.90)。男性每次饮酒量与MS存在线性相关,女性每次饮酒量与MS不存在线性相关。在男性中,饮酒类型与MS不存在相关,饮用白酒、啤酒、葡萄酒和混合酒的男性患MS的OR分别为0.91 (95%CI 0.81～1.03)、0.90 (95%CI 0.75～1.08)、0.85 (95%CI 0.54～1.36)和0.96 (95%CI 0.84～1.10)。相比不饮酒女性,饮白酒或混合酒的女性患MS风险较低,OR值分别为0.74(95%CI 0.56～0.98)和0.78(95%CI 0.66～0.91)。饮酒频率与MS无显著性相关,在男性中P趋势=0.11,在女性中,P趋势=0.31。结论 男性每次饮酒量与MS存在线性相关,每次饮酒量>20 g会增加MS的患病风险;女性每次饮酒量与MS不存在线性相关。
Abstract：OBJECTIVE To examine the association between alcohol consumption and metabolic syndrome(MS) among Chinese men and women aged 18 years and older. METHODS The 2010—2012 China National Nutrition and Health Survey(CNNHS) used multi-stage stratified cluster randomization sampling method to select study participants. Basic information, health-related behaviors and diseases history were collected by questionnaire. Drink information was collected by food frequency questionnaire. Metabolic syndrome was defined according to the updated NCEP ATP III criteria. A total of 102 591 participants aged 18 years and older were included in the analysis. Logistic regression model was performed to examine the association between alcohol consumption and MS. Restricted cubic spline(RCS) was performed to explore the dose response relation of alcohol intake and MS. RESULTS The drink rate was 33.66% in Chinese adults aged 18 years and older. Compared with non-drinkers, men who consumed≤20 g/time had a lower MS prevalence(OR=0.77,95%CI 0.66-0.90). There was a linear dose response association between alcohol intake and MS among men but not among women. In men, there was no association between drinking type and MS. The OR of MS were 0.91(95%CI 0.81-1.03), 0.90(95%CI 0.75-1.08), 0.85(95%CI 0.54-1.36), and 0.96(95%CI 0.84-1.10) among men who consumed liquor, beer, wine, and mixed liquor. Compared with non-drinkers, women who drink liquor or mixed liquor had a decrease MS prevalence. The OR were 0.74(95%CI 0.56-0.98) and 0.78(95%CI 0.66-0.91). The association between drinking frequency and MS had no statistical significance and the P-trend was 0.11 in men and 0.31 in women. CONCLUSION There is a linear dose response association between alcohol intake and MS among men but not in women. Men consumed >20 g/time have an increased MS prevalence.
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基本信息:
DOI：10.19813/j.cnki.weishengyanjiu.2019.04.001
中图分类号:R589
引用信息:
[1]李亚茹,赵丽云,于冬梅,等.中国成人饮酒与代谢综合征的关系[J].卫生研究,2019,48(04):531-536.DOI:10.19813/j.cnki.weishengyanjiu.2019.04.001.
基金信息:
国家卫生和计划生育委员会医改重大项目-中国居民营养与健康状况监测(2010—2012年)
2018-06-14
2018
2019-04-30
2019-10-18
2019
2
2019-07-30
2019-07-30