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随着社会的老龄化,神经退行性疾病的发病率呈逐渐上升的趋势,其会带来巨大的生理痛苦和社会负担。近年来,小胶质细胞在神经退行性疾病中的作用越来越受到重视。本文就小胶质细胞的特性以及小胶质细胞在阿尔茨海默病和帕金森病发生发展过程中的激活、吞噬、炎性作用等方面进行了综述,阐述了目前小胶质细胞在神经退行性疾病中的主要研究机制。
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基本信息:
DOI:10.19813/j.cnki.weishengyanjiu.2015.06.035
中图分类号:R741
引用信息:
[1]王茜,程雪娇,李学敏,等.小胶质细胞在慢性神经退行性疾病中的作用研究进展[J].卫生研究,2015,44(06):1023-1027.DOI:10.19813/j.cnki.weishengyanjiu.2015.06.035.
基金信息:
国家自然科学基金(No.81472984,81001245); 2013年度山西医科大学科技创新基金(No.01201301); 山西省卫生厅科研课题(No.201301082)
2015-03-11
2015
2015-05-26
2015-05-26
2015
1
2015-11-30
2015-11-30